CFAR Molecular Virology Lab / Resistance Lab

You are here

This well-established lab is supported by the Case Western Reserve University CFAR under the supervision of Dr. Eric Arts, Ph.D. The laboratory plays a pivotal role in the care and monitoring of HIV patients both at the JCRC and other research institutions in the country.

The lab carries out HIV-1 drug resistance testing for collaborative research as well as for patient care. To this end, the lab is well equipped with state-of-the-art equipment including a high throughput ABI 3730xl sequencer that is capable of running 96 samples at a time. While the ABI machine is capable of detecting polymorphisms when at about 20-30%, the lab has a multiplex machine that is capable of detecting polymorphisms when present at very low frequencies as low as 1% in the population.

The lab is organized according to WHO guidelines and is VQA-certified. The tissue culture BL-2 lab is well equipped with two laminar flow hoods, refrigerated and non-refrigerated centrifuges for sample processing, as well as incubators for cell culture.