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Joint Clinical Research Centre (JCRC) is a Centre of Excellence that was started by H.E. President Yoweri Kaguta Museveni in 1990 to address the very serious problem of HIV/AIDS, which was at its peak by that time.

The institution is a limited liability, not for profit, Non-Governmental Organisation (NGO), which was initiated by a collaborative effort of: 

  1. Ministry of Health - primarily responsible for policy
  2. Ministry of Defence - which provided the infrastructure
  3. Makerere University Medical School (currently College of Health Sciences) - which provides some of the researchers with whom JCRC works.

At its inception, the centre was supported by a grant from the Ugandan Government used to renovate the initial building and provide basic equipment to start work.

Over the past years, various institutions such as WHO, CWRU, Family Health International, US National Institutes of Health, University of California San Francisco, Johns Hopkins University, the Institute of Tropical Medicine in Antwerp and in Hamburg, EDCTP, MRC, have partnered with the JCRC to obtain several research grants to study HIV, tuberculosis (TB), malaria and other tropical diseases.

The centre's core funding sources mainly come from funding bodies which support collaborative biomedical research and / or antiretroviral therapy roll-out programs.

These include the United States Agency for International Development (USAID) under the US Presidential Emergency fund for Fighting HIV/AIDS (PEPFAR), the European Developing Countries Clinical Trials Partnership (EDCTP), National Institutes of Health (NIH), among others.

The centre also generates revenue from private services at the Clinic, Laboratory, pharmacy and Training services.